CURRICULUM VITAE

Hematology & Oncology

California State License No. C54469

Sutter Medical Group 2800 L Street, Suite 260 Sacramento, CA 95816 Phones (916) 453-3300 Fax: (916) 453-3313 [email protected]

Education:

September 1987 - November 1994 M.D.

Lebanese University Faculty of Medicine Beirut-Lebanon

September 1985 - September 1987 Basic Sciences Lebanese University Beirut-Lebanon

September 1982 - August 1985 Secondary School Essor College Beirut-Lebanon

Research Offices Sutter institute for Medical Research 2801 Capitol Avenue Suite 210 Sacramento, CA 95816 Phone: (916) 733-8930 Fax:(916)733-8913

2801 Capitol Avenue Suite 400 Sacramento, CA 95816 Phone: (916) 453-5898 Fax: (916) 733-8968

Clinical Experience:

July 2011 - Present

Hematology/BMT

Sutter Medical Group

Department Hematology - Oncology

2008-2011 Fellow Physician

University of Arkansas for Medical Sciences Department of Hematology-Oncology

2003-2008 Assistant Professor

Myeloma Institute for Research and Therapy, Bone Marrow Transplant Unit University of Arkansas for Medical Sciences

2001-2003 Resident Physician

University of Arkansas for Medical Sciences Department of Internal Medicine

2000-2001 Intern

University of Arkansas for Medical Sciences Department of Internal Medicine

1997-2000

Fellow Research Physician

University of Arkansas for Medical Science

ACRC, Bone Marrow Transplant Unit

1995-1997 Resident Physician

Lebanese University Faculty of Medicine, Deportment of internal Medicine

Clinical Experience:

1994-1995 Intern

Lebanese University Faculty of Medicine Department of Internal Medicine

Honors:

November 30, 2004

Recognized by the Press Ganey Surveys as an exceptional caregiver and received certificate of appreciation

1996-1997

Chief Resident at St. George Hospital, Beirut, Lebanon 1993-1994

Best Intern (Internal Medicine) at St. George Hospital, Beirut, Lebanon

Membership:

Member of AR Medical Society since July 2004 Member of SWOG as of 06/02/04 Member of AMA

Licensure & Certifications:

American Board certified in internal Medicine In October 2003 American Board Certified Hematology in November 2011 American Board Certified Oncology November 201 1 ECFMG Certificate; Number #0-511 -921-9. Valid Indefinitely ACLS certified and up to date AR State Medical Board License CA State Medical Board License HIPPS compliance

Fraud-awareness - Professional compliance

Publications:

1. Cytopen'ta, Dysplasia, and Monocytosis: A Precursor To Chronic Myelomonocytic Leukemia or a Distinct Subgroup? Cose Reports and Review of Literature, Zeba N. Singh, Ginell R. Post, Elias Kiwan, Anne-Marie Maddox. Clinical Lymphoma, Leukemia, and Myeloma 2011; Vol. 11, No. 3, 293-7.
2. Neoadjuvant Systemic Treatment of Breast Cancer: Issam Makhoul and Elias Kiwan. Journal of Surglal Oncology 201 1; 103:348-357.
3. Cetuximab-Reloted First Infusion Reaction Rate in Cancer Patients, E. Kiwan, I. Makhoul, E. Siegel, L. Hutchins, A. Maddox, R. Govindarajan, M. Safar, E. Kiwan. ASCO Abstracts: Chicago, June 3^rd- 5^lh, 20 U.
4. Immune Reconstituthn Inflammatory Syndrome (IRIS) From Invasive Aspergillosis (IA) In Patients (Pts) With Hematological Cancer (Hem-ca); A New Entity With Clinical ond Research Implications. Miceli M¹, Grazziutti M>, Woods G², Krishna $', Kiwan E¹, Syed N>, Barlogie B>, Anaissie E>.

Publications cont:

5. Completion of Premaintenance Phases in Total Therapies 2 and 3 Improves Clinical Outcomes in Multiple Myeloma: An Important Variable to be Considered in Clinical Trials Designs, Barlogie B. Maessler J. Pineda-Roma M. Anaissie E. van Rhee F. Kiwan E. Steward D. Gurley J. Jenkins B. Crowley J. Cancer. 11 2(1 2):2720-5, 2008 Jun 15.
6. Hyperammonemia and encephalopathy in patients with multiple myeloma. Talamo G, Cavallo F, Zangari M, Barlogie B, Lee CK, Pineda-Roman M, Kiwan E, Krishna S, Tricot G, American Journal of Hematology. 82 (5)i414-5, 2007 May
7. Oral mucositis in myeloma patients undergoing melphalan-based autologous stem cell transplantation: incidence, risk factors and severity predictive model. Grazziutti ML, Dong L, Miceli MH, Krishna SG, Kiwan E, Syed N. Fassas A, van Rhee F, Klaus H, Barlogie B, Anaissie EJ. Bone Marrow Transplantation. 38(7}:501-6, 2006 Oct.
8. Clinical and biological features of multiple myeloma involving the gastrointestinal system, Giampaolo Talamo, Federica Cavallo, Maurlzio Zangari, Bart Barlogie, Choon-Kee Lee, Mauricio Pineda-Roman, Elias Kiwan, Somashekar Krishna, Guido Tricot. Haematologica. 91(7):964-7, 2006. Jul.
9. Thalidomide and hemalapaietk-cell transplantation for multiple myeloma. Barlogie B. Tricot G. Anaissie E. Shaughnessy J. Rasmussen E. van Rhee F. Fassas A. Zangari M. Hollmig K. Pineda-Roman M. Lee C. Talamo G. Thertulien R. Kiwan E. Krishna S. Fox M. Crowley J. New England Journal of Medicine. 354(10)r 1021-30, 2006 Mar 9.
10. Metronomic chemoimmunolherapy in a patient with refractory Waldenstrom's macroglabulinemia, Fassas AB. Kiwan E. Roberts J. Burr T. Tricot G. Anaissie E. Barlogie B. Leukemia & Lymphoma 46(11): 1675-7, 2005 Nov.

1 1. Fungal Infections in the patient with Cancer. Elias J. Anaissie, Tahsine H. Mahfouz, Elias N. Kiwan. Clinical Mycology Book. Ed: Anaissie E.J., McGinnls M.R., Pfaller M.A. 1" Edition. Jul. 2002.

1 2. Hyalohyphomycosis. Maria Cecilia Dlgnani, Elias N. Kiwan, Ellas J.

Anaissie. Clinical Mycology Book. Ed: Anaissie E.J., McGinnis M.R., Pfaller M.A. 1st Edition Jul. 2002.

1 3. Hyalohyphomycosis: Systemic and Superficial Diseases, Elias N. Kiwan & Elias J. Anaissie. Antimicrobial Therapy and Vaccines. Ed: Yu V.L., Merigan T.C. 2^nd Edition. June 2002.

14. The Clinical Spectrum of Stenotrophamonas (xanthomanas) Mallophilia Respiratory Infection. Shahe E. Vartlvarlan, Elias J. Anaissie, Elias N. Kiwan, & Konstantlnos A. Papadakls. Seminars in Respiratory & Critical Care Medicine. Problems in Pulmonary Pathogens: Louis B. Rice, M.D. 21 (4):349-355. July 2000.

Publications cont:

15. Nosocomial Stenotrophomonas Maltophila Infections: Spectrum of Disease, Outcome Variables, and Literature Review, Shahe E. Vartlvarian, Elias J. Anaissie, Elias N. Kiwan, and Konstantinos A. Papadakls. Archives of Internal Medicine. Mar. 2000.
16. Overviews of Infections in Patients Treoted with Fludorabine Analogs, Elias J. Anaissie & Elias N. Kiwan. UpToDate, ed; Burton DR, UpToDate, Inc. 8 (3). Updated x4.    Mar. 2000.
17. Prevention and Early Treatment of Infecfions in Palienls wi/h Cancer. Ellas N. Kiwan & Ellas J. Anaissie. ASCO Education Session, Book 99, ASCO 160-168.     Sept. 1999.
18. Management of Febrile Neutropenia in Patients with Hematological Malignancies; An Update, Elias J. Anaissie & Elias N. Kiwan. ASH Education Book, Book 1999 ed. ASH, 455-463. Sept. 1999.
19. Fungal Infections Complicating Neoplastic Diseases. Elfas N. Kiwan & Elias J. Anaissie. Fungal Diseases of the Lung: Eds Sarosl G.A., Davies S. F., 3^rd Edition, 219-238. Sept. 1999.
20. Prophylaxis of Infections in Bone Marrow Transplant Recipients, Elios J. Anaissie & Elias N. Kiwan. UpToDate, ed: Burton DR, UpToDate, Inc. 7 (3), 1-23. Updatedx4. Sept. 1999.
21. Overviews of Infections following Bone Marrow Transplantation. Ellas N. Kiwan & Ellas J. Anaissie. UpToDate, ed: Burton DR, UpToDate, Inc. 7(3), Updated x4. Aug. 1999.
22. Evaluation for Infection before Bone Marrow Transplantation. Elias N. Kiwan & Elias J. Anaissie. UpToDate, ed: Burton DR, UpToDate, Inc. 7(3), Updated x4. Mar. 1999.
23. Demar/aceous and Non-Pigmented Fungi: Invasive and Systemic Diseases. Elias N. Kiwan & Ellas J. Anaissie. Antimicrobial Therapy and Vaccines. Ed: YuV.L., Merigan T.C. 1^st Edition, 1102-1108. Jan. 1999.
24. Fungal Infections in Hemafo/og/ca/ Mo/ignonci'es! Advances in Laboratory Diagnosis and Therapy. Elias N, Kiwan and Elias J. Anaissie. Reviews in Clinical and Experimental Hematology, 7, p: 57-83. Jul. 1998.

Abstract Presentations:

1.  Velcade-Reloted Recovery of Renal Function After Two Years of

Hemodialysis Dependence. Klaus A Hollmig, Mauriclo Plneda-Romon, Elias Kiwan, Bart Barlogie.

UAMS, Little Rock, AR                                                                                ASH 2008

Abstract Presentations cont:

2. Ninety Percent Sustained Complete Response (CR) Rate Projected 4 Years after Onset of CR in Gene Expression Profiling (GEP)-Defined low-Risk Multiple Myeloma (MM) Treated with Total Therapy 3 (TT3): Basis for GEP-Risk-Adapted TT4 and TT5. Bart Barlogie, MD, PhD, Ellas J. Anaissie, MD, John D. Shaughnessy Jr., PhD, Frits van Rhee, MD, PhD, Mauricio Pineda-Roman, MD, Jeff Haessler, MD, Klaus A. Holimig, MD, Yazan Alsayed, MD, Sarah Waheed, MD, Monica Graziutti, MD, Elias Kiwan, MD and John Crowley, PhD

UAMS Little Rock, AR                                                                                 ASH 2008

3. Rapidly Cycled Aggressive Lymphoma-Like Therapy (HD-DTPACE) for
   Salvage of Patients with Advanced Multiple Myeloma (MM), V
   Arzoumanian, MD; B Barlogie; M Pineda-Roman; K Holimig; E Anaissie;
   M Z; S Krishna; E Kiwan; G Tricot; A Mohluddln and F Van Rhee.
   UAMS, Little Rock, AR                                                                                 ASH 2006
4. Validation of Serum Aspergillus Ga/acfomannan Index as a Surrogate Endpoint for Outcome of Invasive Aspergillosis: Clinical and Research Implications, G Woods, M Miceli, M GrazziuttI, S Krishna, N Syed, E Kiwan, M Rahman, B Barlogie and E Anaissie.

UAMS, Little Rock, AR                                                                                ASH 2006.

5. Immune Reconstruction Inflammatory Syndrome (IRIS) with Invasive
   Aspergillosis (IA) in Patients (pts) with Hematological Cancer (Hem-Ca):
   Clinical and Research Implications. M Miceli, M Grazziutti, G Woods, S
   Krishna, N Syed, E Kiwan, M Rahman, B Barlogie and E Anaissie.
   UAMS, Little Rock, AR                                                                                 ASH 2006.
6. Outcome of Invasive Aspergillosis (IA) in 30 Patients with Hematological Cancer (Hem-Ca): Immunity Is (Almost) Everything. M Miceli, M Grazziutti, G. Woods, J Diaz, S Krishna, E Kiwan, N Syed, B Barlogie, and E. Anaissie.

UAMS, Little Rock, AR                                                                                ASH 2006.

7. High-Dose Melphalan (MEL)-Based Autotransplants (AT) for Multiple Myeloma (MM): the Arkansas Experience since 1989 in >2800 Patients. Mauricio Pineda-Roman, Klaus Holimig, Ellas Anaissie, Frits van Rhee, Antje Hoerlng, Maurizlo Zangari, Somashekar Krishna,¹ Elias Kiwan, Guido Tricot, Abid Mohiuddin, John Crowley, Bart Barlogie.

UAMS, Little Rock, AR                                                                                ASH 2006

8. Melphalan Mg/Kg Dose is an Independent Survival Factor in Patients
   Receiving Total Therapy 2 far Multiple Myeloma. Elias Anaissie,
   Varant Arzoumanian, Monica Grazziutti, Marlsa Miceli, Frits van Rhee,
   Mauricio Pineda-Roman, Klaus Holimig, Abid Mohiuddin, E Kiwan,
   Nayyar Syed, Somashekar Krishna, Guido Tricot, Bart Barlogie.
   UAMS, Little Rock, AR                                                                                ASH 2006
9. Serum Aspergillus Galactomannan Index (GMI), a Validated Surrogate Endpoint (SEP) in 30 Patients (pts) with Invasive Aspergillosis (IA): Clinical and research Implications. Woods G, Miceli M, Grazziutti M, Krishna S, Syed N, Kiwan E, Barlogie B, Anaissie E.

UAMS, Little Rock, AR                                                                                ASH 2006

Abstract Presentations cont:

I0, Spontaneous Resolution and Immune Re constitution Inflammatory Syndrome
(IRIS) in Patients (pts) with Invasive Aspergillosis (IA): Immunity is (olmost)
everything. Miceli M^l, Grazziutti M¹, Woods G², Dioz JA¹, Krishna S¹,
Kiwan E', Syed N¹, Borlogle B¹, Anaissie E^l. UAMS, MIRT¹ ond
Deportment of Pathology², Little Rock, AR                                           ASH 2006

1 1. A//menfary /rocf mucos/ffs in myeloma potients undergoing melpholon-based autologous stem cell transplantation: incidence, risk factors and a severity prediction model. Monica L, Grozziutti, Li Dong, Marlsa H. Miceli, Elias Kiwan, Aihanasios Fassas, Frits VonRhee, Bart Barlogie and Elios J. Anaissie.

UAMS Little Rock, AR                                                                                 ASH 2004

1 2. Risk Stratification os a Novel Approach lor Prevention of Invasive Fungol Infections. Elios N. Kiwan & Elias J. Anaissie. Education Book: Internationol Society /or Humon ond Animai Mycology (ISHAM), Buenos Aires, Argentina. May 23-24, 2000.

Slides and Poster preparations:

1. Invasive Fungal Agents ond New theropeutk Agents, Little Rock, AR, Jon 2004
2. Internationol Symposium on Humon and Animal Mycology, Buenos Aires, Argentina, May 2000.
3. Te/econ/erence on Emergence of Nosocom/o/ Fungal Infections, Teleconference Network of Texas, April 2000.
4. Lecture ond a Poster on "Prevention of Invasive Aspergillosis in Immunocompromised Patient" in Sporanox International Symposium in Cannes/ France. Apr 2000.
5. Interscience Conference on Antimicrobials Agents and Chemotherapy, ICAAC 1998, 1999, & 2000.
6. Infectious Diseases Society of America, 36^,h Meeting iDSA, 1999.
7. Focus on Fungal Infections, Atlanta, GA, 1999.
8. Lebanese Infectious Diseases Society, Beirut, Lebanon, 1999

language fluency: Arabic (spoken and written) English (spoken and written) French (spoken ond written)