Sutter East Bay Neuroscience Institute

CURRICULIM VITAE

David C. Bonovich, MD

Position:

Affiliated Neurological Consultant, San Francisco 49ers Professional Football Team, 2023 - present

                        Director – Sutter East Bay Neuroscience Stroke Center, 2008-2022

                        Director - Neurointensive Care Unit, 2008-2022

                        Director, Neurointerventional Program, and Former Director, Cerebrovascular Disease Programs Sutter East Bay Neuroscience Institute 2008-2022

                        Eden Medical Center

                        20101 Lake Chabot Road – Room 2728

                        Castro Valley, California 94546

Former Medical Director, San Ramon Regional Medical Center Stroke  Program

                        6001 Norris Canyon Rd, San Ramon, CA 94583

Former Oakland Raiders Professional Football Team Unaffiliated Neurological Consultant 2019-2021

Contact:          Mobile:            (510) 727-2790

                        FAX:    (510) 727-3393

                        Email:  [email protected]

EDUCATION

LICENSE, CERTIFICATION

1990                Medical Licensure, California

Board Certification, Neurology

2006                Board Recertification, Neurology Medical Licensure, Oregon

2007                Certification: Cordis Enterprise Stent Course

Certification: Cordis Glue Embolization Course

2008                California Fluoroscopy Supervisor and Operator’s License

PRINCIPAL POSITIONS HELD

OTHER POSITIONS HELD CONCURRENTLY

HONORS AND AWARDS

1978-1980:      Member Beta Beta Beta Biological Honor Society

1980:               cum laude graduate, Towson State University, Towson MD

1989:               Richard Mason Award as the Outstanding Intern in the 1989 class, Letterman Army Medical Center, Presidio of San Francisco, San Francisco CA

1995:               Outstanding Teaching Award from the Department of Family Practice, Womack Army Medical Center, Fort Bragg NC

1995:              Outstanding Teaching Award from the Physician’s Assistant class of 1995, Fort Bragg, NC

KEYWORDS/AREAS OF INTEREST

Cerebrovascular disease, aneurysm, subarachnoid hemorrhage, intracerebral hemorrhage, ethnicity and vascular disease, Asian vascular disease, Interventional Neuroradiology, multi-system trauma, traumatic brain injury, intracranial pressure, spinal cord injury, critical care medicine

PROFESSIONAL ORGANIZATIONS

Memberships

1996-               Bay Area Stroke Society

1998-               Society of Critical Care Medicine

2003-               Neurocritical Care Society

2004-               Federation of Chinese American and Chinese Canadian Medical Societies

2014-              Bay Area Neurocritical Care Society (BANCS)

Service to Professional Organizations

1999-2009       American Board of Psychiatry and Neurology        Examiner for Part II

Oral Boards

2003-2010       Neurological Certification Board, Hong Kong SAR         Outside Examiner

SERVICE TO PROFESSIONAL PUBLICATIONS

Ad Hoc reviewer         American Journal of Cardiology

Ad Hoc reviewer         Medical Journal of Hong Kong

Ad Hoc reviewer         Journal of Neurology Neurosurgery and Psychiatry

Ad Hoc reviewer         Yonsei Medical Journal

Reviewer                     Neurocritical Care

Reviewer                     Neurology

INVITED PRESENTATIONS

International

1998                Recent Advances in the Treatment of Thrombotic Stroke, Hong Kong SAR (Invited Speaker)

                        St. Paul’s Hospital, Hong Kong SAR (Guest Speaker)

1999                2^nd Annual Scientific Meeting of the ASITN and Joint Section of          Cerebrovascular Surgery (Platform Presentation)

2000                Hong Kong Stroke Symposium and Workshop 2000, Hong Kong SAR

                        (Overseas Organizer, Invited Speaker)

2001                St. Paul’s Hospital CT and MRI Imaging Centre: Symposium on Acute Stroke Management, Hong Kong SAR

                        Hong Kong Stroke Symposium and Workshop, 2001, Hong Kong SAR

(Overseas Organizer, Invited Speaker)

                        University of Hong Kong, Neurology Division (Invited Speaker)

2002                3^rd Hong Kong Stroke Symposium and Workshop 2002, Hong Kong SAR

(Overseas Organizer)

2003                4^th Hong Kong Stroke Symposium and Workshop, Hong Kong SAR (Overseas Organizer, Invited Speaker)

                        Adventist Hospital of Hong Kong, Vascular Awareness in Hong Kong Press Release

2004                International Conference on Cardiovascular Clinical Trials and Pharmacotherapy, Hong Kong SAR (Invited Speaker)

                        First International Conference on Intracranial Atherosclerosis, Hong Kong SAR (Chairperson, Plenary Session)

5^th Hong Kong Stroke Symposium and Workshop, Hong Kong SAR (Overseas Organizer, Invited Speaker)

2005. Indo-US Symposium on Cerebrovascular Disease, New Delhi, India:

IV Thrombolysis in Acute Stroke Treatment (Invited Speaker)

2006. UCSF-Hong Kong Epilepsy Symposium, Hong Kong SAR (Overseas Organizer)

Hong Kong Epilepsy Society, Hong Kong SAR

(Guest Speaker: International Collaboration in the Treatment of Epilepsy)

2^nd International Conference on Intracranial Atherosclerosis, San Francisco, California – Co-Chairman and Organizer

1^st Seoul National University International Stroke Symposium, Seoul Korea (Co-Moderator, Session I; Invited Speaker)

2007                Symposium on Intracranial Atherosclerosis and the TOSS II Trail, San

Francisco, California (Invited Speaker)

Gladstone Institute, University of California San Francisco: Asian Brain Health Initiative Symposium: Diagnosis, Mechanisms, and Treatment of Neurodegenerative Disease, Beijing China (Invited Speaker)

2007. Asian Pacific Coalition Against Stroke, Manila Philippines (Invited Speaker)

                        3^rd International Conference on International Atherosclerosis, Seoul Korea (Member, International Organizing Committee; Invited Speaker)

2009. 4^th International Conference on Intracranial Atherosclerosis, Beijing China (Member, International Organizing Committee; Invited Speaker)

Tiantan International Stroke Conference, Beijing China (Invited Speaker)

Stroke Society of the Philippines, Manila Philippines (Invited Speaker)

2010.       First World health Forum & Cooperation Conference,    Shanghai, China (Invited Speaker)

2011. Quadricentennial Neuroscience Summit,

University of Santo Tomas, Manila, Philippines (Invited Speaker)

Philippine National Stroke Certification Course, Invited Speaker

5^th International Conference on Intracranial Atherosclerosis, Valladolid Spain (Member, International Organizing Committee; Invited Speaker) 

University of Santo Tomas Qudracentinial Stroke Conference (Invited Speaker): Carotid Endarterectomy versus Stenting for Symptomatic Carotid Artery Stenosis; Updates on Endovascular Treatment and Neurocritical Care of Ruptured aneurysms; Advancements and in the Recognition and Management of Intracranial Stenosis

Philippine Stroke Certification Course (Invited Speaker): Emerging Therapies in Acute Ischemic Stroke and Hemorrhagic Stroke; Medical Management of Subarachnoid Hemorrhage; Endovascular Management of Intracranial Aneurysms

5^th International Conference on Intracranial Atherosclerosis, Valladolid Spain (Organizing Committee and Invited Speaker): Future directions in ICAS. Main unresolved clinical problems. Boosting international research collaboration in ICAS.

2013                6^th International Conference on Intracranial Atherosclerosis (Organizing Committee): Session Chair: Epidemiology, Risk Factors, and Prognosis; Invited Speaker: What’s on the Horizon for Endovascular Treatment of Acute Ischemic Stroke     

                        Society of Vascular and Interventional Neurologists 6^th Annual Meeting (Invited Speaker): Balloon Guides: There is no substitute in Acute Stroke Thrombectomy

2014                7^th International Conference on Intracranial Atherosclerosis,

                        Chengdu, China (Organizing Committee and Invited Speaker):

                        Global Importance of Intracranial Atherosclerosis

                        Update on the Treatment of Carotid Artery Disease      

2016                8^th International Conference on Intracranial Atherosclerosis,

                        Cheju Island, South Korea (Organizing committee and invited Speaker

                        The WEAVE Registry

2019                9^th International Conference on Intracranial Atherosclerosis Los Angeles California (Co-Sponser and Invited Speaker)  

                        ICAD in the United States

2022                10^th International Conference on Intracranial Atherosclerosis, Rotterdam, Netherlands (Organizing Committee and Invited Speaker)

2024                11^th International Conference on Intracranial Atherosclerosis, Manila, Philippines (Organizing Committee and Invited Speaker

Other International Invitations

2001                Visiting Professor, 2^nd Affiliated Hospital of Guangzhou Medical College (March);

                        Visiting Professor, 2^nd Affiliated Hospital of Guangzhou Medical College (December)

2002                UCSF Telesymposium: Video Conference Series: Hong Kong, Singapore, Manila

2003                Visiting Professor, Peking University Health Science Center, Beijing China; October 2003

Visiting Professor, Peking University Health Science Center, Beijing China; December 2003

Visiting Professor, Peking Union Medical College, Beijing China;

Visiting Professor, Fu Wai Hospital, Beijing China

2004. Visiting Professor, 2^nd Affiliated Hospital of Guangzhou Medical College

2006                Visiting Professor, Seoul National University, Seoul Korea

                        Visiting Professor, Asan Medical Center, Seoul Korea

2007                Visiting Professor, Santo Tomas University, Manila Philippines

2009                Visiting Professor, Santo Tomas University, Manila Philippines

                         (Yearly lecture and resident teaching)

National

1998                68^th Annual Physician’s Postgraduate Symposium on Cardiovascular Disease and Stroke (Invited Speaker)

1999                17^th Annual Scientific Sessions for Cardiovascular Nursing;

                        American Heart Association Annual Sampson Symposium (Program Committee, Invited Speaker)

2000                California Radiological Society

2001                The 6^th Annual Vascular & Endovascular Strategies Symposium

2002                American Academy of Neurology: Acute Stroke Management Course

2003                American Heart Association Sampson Symposium (Director, Neurology Section, Invited Speaker)

Thomas Jefferson University, Philadelphia, PA Departments of Neurology/Neurosurgery Grand Rounds;

2004                12^th Conference on Healthcare of the Chinese in North America;

Lander Community Hospital Medical Grand Rounds, Lander Wyoming;

Hot Springs Memorial Hospital, Medical Grand Rounds Thermopolis, Wyoming

Grand Rounds Stony Brook University Hospital, New York

2005. Cardiology Grand Rounds, Swedish Hospital, Seattle Washington

20^th Annual North American Taiwanese Medical Association CME Meeting, San Jose California

Neurology Grand Rounds, Boston University Medical Center

Medicine Grand Rounds, El Camino Medical Center

2006. San Diego Medical Society, San Diego California

Sharps Medical Center, San Diego, California

University of California, Davis, Davis, California: Invited Teacher on Clinical Ward Rounds in Neurology

Boston University Medical Center, Boston Massachusetts

Visiting Professor 23-24^th January

Queens Medical Center, Honolulu Hawaii

Visiting Professor, 9^th-10^th February 2006

2007. Medical Grand Rounds, Chinese Hospital, San Francisco California

34^th Annual Critical Care Symposium: Greater Portland Chapter of the American Association of Critical Care Nurses and the Oregon Chapter of the Society of Critical Care Medicine

Vasoactive Therapy in the Critical Care Setting, Medical Management of Traumatic Brain Injury

Regional Presentations

1998                Neurological Emergencies Course for Critical Care Nurses;

                        Critical Nurses Training Program, UCSF

1999                Santa Clara Valley Hospital (California) Neuroscience Seminar;

University of Chicago Rush Medical School: Neuroscience Grand Rounds

Santa Clara Valley Medical Center (California), Neuroscience Grand Rounds

2000                Santa Teresa Community Hospital (San Jose, California) Grand Rounds

2002                University of California San Francisco, Internal Medicine Grand Rounds, San Francisco General Hospital;

University California San Francisco, Fresno Campus, Medicine Grand Rounds;

St. Luke’s Hospital, San Francisco California Medicine Grand Rounds

2003                Chinese Hospital, San Francisco Department of Medicine Grand Rounds;

University of California San Francisco, Fresno Campus Department of Medicine Grand Rounds;

University of California San Francisco Department of Neurology Grand Rounds;

St. Mary’s Hospital, San Francisco Medical Grand Rounds

California Pacific Medical Center, San Francisco Neuroscience Grand Rounds

2004. Chinese Hospital, San Francisco, Department of Nursing Grand Rounds;

Kaiser Hospital of San Francisco, Resident Lecture

University of California David, Resident/Fellow lecture

2013

                        Grand Rounds: Eden Medical Center: Stroke Update

2014               

                        29^th Annual Sutter Neuroscience Symposium: Medical and Endovascular Management of Aneurysms and Vascular Malformations

                        St Rose Hospital Grand Rounds: Stroke Update

                        Summit Medical Center: Stroke Update: Aneurysms, Vascular Malformations, and Ischemic Stroke

                        Alameda Hospital: Update on Stroke: Endovascular Management of Acute and Chronic Ischemia

2015                Modesto Memorial Medical Center: The Changing Landscape of Stroke

                        Alameda County Emergency Medical Services: The Changing Landscape of Stroke

CME COURSES ATTENDED

1. 2004. Departmental Grand Rounds each week

1999                American Heart Association Sampson Symposium;

2^nd Annual Meeting of the ASITN and Joint Section of Cerebrovascular Surgery

2001                American Academy of Neurology Annual Meeting;

                        American Heart Association International Stroke Meetings

2002                American Academy of Neurology: Acute Stroke Management Course

2003                American Heart Association Annual Sampson Symposium

2007                American Heart Association: International Stroke Conference

2009                American Heart Association: International Stroke Conference

TEACHING and MENTORING

FACULTY MENTORING

During my tenure as Fellowship Program Director at UCSF, I was responsible for reviewing all applications and applicants applying for the Neurovascular and Neurocritical Care Fellowship Program at UCSF. This fellowship program is a 2 year program that involves 1 year of training in critical care medicine, and one year of training in neurovascular and neurocritical care medicine. As the fellowship program director, I interfaced with the fellows directly in clinical teaching and in weekly one-on-one didactic conferences, and by discussing performance evaluations, and career direction. In addition, I met with them informally to discuss other aspects of the fellowship program and their thoughts and ideas regarding their training.

INTERNATIONAL SCHOLARS SUPERVISED

Once I started my fellowship in Interventional Neuroradiology (October 2006), I reduced the amount of mentoring and teaching to residents considerably. I am still taught stroke and critical care primarily to internal medicine, and primary care residents at Legacy Emmanuel Hospital in Portland, Oregon. During this time I was been able to maintain my clinic for Asian patients through Chinese Hospital in San Francisco, and expand my international activities: I have received the title of permanent visiting faculty at the University of Santo Tomas in Manila, Philippines, and continue my efforts internationally regarding intracranial atherosclerosis.

Other Teaching/Mentoring

Consultant, Stryker Neurovascular Brain Training Course: Neurointerventional Case Reviews: Case reviews with Stryker engineers, sales and marketing, and territory managers once each quarter

Peer Reviewed Publications

1. 1. 1. 1. Hemphill JC, Bonovich DC, Lavrentios B, Manley GT, Johnston SJ: The ICH Score. A simple, reliable grading scale for intracerebral hemorrhage. Stroke 2001; 32: 891-897.

1. 1. 1. 2. Vates GE, Wang KC, Bonovich DC, Dowd CF, Lawton, MT: Bowhunter’s syndrome caused by cervical disc herniation: Case Report. J. Neurosurgery 2002; 96 (1 suppl): 90-93.

1. 1. 1. 3. Tsao J, Gean AD, Glenn OA, Bonovich DC: Hyperdense MCA resolved after tPA. Neurology 2002; 58: 1512.

1. 1. 1. 4. Tsao J, Hemphill JC, Johnston SC, Smith WS, Bonovich DC: Initial Glasgow Outcome Scale score (GCS) helps predict outcome following thrombolysis for posterior circulation stroke. Archives of Neurology 2005; 67: 1126-1129.

1. 1. 1. 5. Smith WS, Tsao JW, Billings ME, Johnston SC, Hemphill, JC, Bonovich DC, Dillon, WP: Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia. Neurocritical Care 2006; 4: 14-17.

1. 1. 1. 6. Flint AC, Hemphill JC, Bonovich DC: Therapeutic hypothermia after cardiac arrest: performance characteristics and safety of surface cooling with or without endovascular cooling. Neurocritical Care 2007;7(2):109-18.

1. 1. 1. 7. Nahab F, Cotsonis G, Lynn M, Feldmann E, Chaturvedi S, Hemphill JC, Zweifler R, Johnston K, Bonovich D, Kasner S, Chimowitz M; WASID Study Group: Prevalence and prognosis of coexistent asymptomatic intracranial stenosis. 2008 Mar;39(3):1039-41.

Non-Peer Reviewed Publications

1. Bonovich DC: Cerebral Aneurysms. Chapter 70 in: Weiner-Kornish J (ed.): Critical Care Secrets. 2 ed. Hanley & Belfus, Inc. Philadelphia, 1998.

2. Bonovich DC, Nicholau D: Head Trauma. Chapter 76 in: Weiner-Kornish J (ed.): Critical Care Secrets. 2ed. Hanley & Belfus, Inc. Philadelphia, 1998.

3. Bonovich DC, Nicholau D: Brain Death. Chapter 68 in: Weiner-Kornish J (ed.): Critical care Secrets. 2 ed. Hanley & Belfus, Inc. Philadelphia, 1998.

4. Bonovich DC, Nicholau D: Cerebrovascular Accidents. Chapter 71 in: Weiner-Kornish J (ed.): Critical Care Secrets. 2ed Hanley & Belfus, Inc. Philadelphia, 1998.

5. Bonovich DC: Stroke. Chapter 69 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

6. Bonovich DC, Kelly BJ: Landry-Guillain-Barre Syndrome. Chapter 70 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

7. Bonovich DC, Kelly BJ: Myasthenia Gravis. Chapter 71 in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

8. Palestrant D, Bonovich DC: Head Trauma. Chapter 73 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

9. Jarquin-Valdivia AA, Bonovich DC: Coma. Chapter 65 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

10. Jarquin-Valdivia AA, Bonovich DC: Brian Death. Chapter 66 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

11. Bonovich DC: Status Epilepticus. Chapter 67 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia, 2002

12. Palestrant D, Bonovich DC: Cerebral Aneurysms. Chapter 68 in: in: Weiner-Kornish J (ed.): Critical Care Secrets. 3^rd ed. Hanley & Belfus, Inc. Philadelphia. (2002)

13. Bonovich DC, Hemphill JC: Intensive Care Management of Ischemic Stroke and Intracerebral Hemorrhage. In: Neurosurgical Intensive Care. Andrews B (ed). McGraw-Hill Co. San Francisco, 2003

14. Bonovich DC: Arterial Thrombosis, Cerebral. In Aminoff MJ, Daroff RB (eds): Encyclopedia of the Neurological Sciences. Elsevier Sciences, 2003

15. Bonovich DC: Embolism, Cerebral. In Aminoff MJ, Daroff RB (eds): Encyclopedia of the Neurological Sciences. Elsevier Sciences, 2003

16. Bonovich DC: Brain Death. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

17. Bonovich DC: Coma. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

18. Bonovich DC: Head Trauma. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

19. Bonovich DC: Landry-Guilain-Barre Syndrome. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

20. Bonovich DC: Myasthenia Gravis. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

21. Bonovich DC: Status Epilepticus. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

22. Bonovich DC: Stroke.  In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

23. Bonovich DC: Cerebral Aneurysms. In: Weiner-Kornish J (ed.): Critical Care Secrets. 4^rd ed. Hanley & Belfus, Inc. Philadelphia, (in press)

Other Non-Peer Review Publications

1. Gress DR, Bonovich DC: Thrombolysis for acute stroke: A new era in treatment. Am Fam Phys 1997; 55:2590-2591.

2. Nguyen-Huynh M. Bonovich DC: Stroke in Asian and Pacific Islanders. Stroke Rounds 2004; Vol.2, Issue 5

Abstracts

1. Bonovich DC, Hemphill JC, Gress, DR, Johnston, SC, Dowd CF, Higashida RT, Smith WS: Treatment of vasospasm following subarachnoid hemorrhage with balloon angioplasty. Neurology 1998; 50 (suppl. 4): P06.118.

2. Johnston SC, Smith WS, Dowd CF, Higashida RT, Lawton MT, Halbach VV, Bonovich DC, and Gress DR, “De novo dural arteriovenous fistulae caused by cerebral sinus thrombosis: case report,” poster presentation at Joint Section on Cerebrovascular Surgery and The American Society of Interventional and Therapeutic Neuroradiology Annual Meeting, 1998.

3. Hemphill JC, Bonovich DC, Manly GT, Johnston SJ: Using prognostic models to select intracerebral hemorrhage patients for acute intervention. Stroke 2000; 31:307 (P53)

4. Tsao JC, Hemphill, JC, Smith WS, Bonovich DC: Outcomes following thrombolysis for posterior circulation stroke. 6^th International Conference on Acute Stroke and Thrombolytic Therapy. Great Barrier Reef Australia (slide presentation).

5. Tsao JC, Gean AD, Glenn OA, Bonovich DC: Hyperdense middle cerebral artery sign resolved following t-PA. 6^th International Conference on Acute Stroke and Thrombolytic Therapy. Great Barrier Reef Australia (slide presentation). 2001

6.  Besmertis L, Bonovich DC, Hemphill JC: The role of hypotension in secondary brain injury after intracerebral hemorrhage. Stroke 2001; 32:358 (P108).

7. Tsao JW, Smith WS, Hemphill JC, Bonovich DC: Outcomes following thrombolysis for posterior circulation stroke. Stroke 2001; 32: 373 (P189)

8. Ko NU, Bonovich DC, Gress DR, Smith WS: Determining cerebral hyperperfusion following angioplasty and stenting using xenon computed tomography AAN Poster P04.019

9. Kao A, Bonovich DC, Solbrig M, Jay CA.  Wound botulism among “skin-popping” injection drug users:  a case series, 1991-2002.  Neurology 60(suppl1):A104 (2003).

10. Cree B, Lamb S, Chen A, Bonovich DC, Islar J, Waubant E, Genain C: Tolerability and effects of Rituximab (Anti-CD20 Antibody) in neuromyelitis optica (NMO) and multiple sclerosis (MS). Neurology 62(suppl.5): P06.090 (2004).